Small Molecule


  • CMIC Small Molecule services

Supported Small Molecule Studies

  • Validated single methods with up to 6 analytes
  • Compounds containing radioactive isotopes
  • Compounds that are highly absorbent (non-specific binding) or have poor stability
  • Complex matrices: ocular tissue, brain tissue, human tumor tissue, skin patch
  • Provide prefilled transfer containers to support sample stability at sites

Small molecule bioanalysis is a well established science, but not all small molecule studies are straight forward – CMIC is a partner that can handle any situation.

Complex Studies

Up to 6 analyte methods, Radioactive compounds, Hi-absorbance compounds, Tissue methods specialist, Pre-filled transfer containers

Services

Quantitation
Qualitative
Metabolite confirmation

Scientists

Same PI for method development, validation and sample analysis, 2nd analyst performs QC during critical steps, Average 12 yrs. of experience


Instrument Platforms

CMIC delivers Accuracy and flexibility across multiple platforms including: • LC-MS/MS • UHPLC-UV • UHPLC-FLR • QTRAP 6500 • ECL MSD Sector Imager 6000 • MSD S600 • ELISA absorption, fluorescence • Gyrolab XP Workstation • qPCR • Ion Torrent • GC/MS • Orbitrap Q


Drug Development Stages

Bioanalysis for non-clinical and clinical stages of drug development


Method
Development
Method
Validation
Method
Transfer
Cross
Validation
Sample
Analysis

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